Selected stromal markers of osteoblastic PCa indicate a conserved mechanism of tumor cells to induce a stromal pre-metastatic signature with high potential prognostic or diagnostic value.
This study highlights the functional application of an anti-MCAM mAb to target prostate cancer bone metastasis.
This study highlights a functional role for CRIPTO and GRP78 in PCa metastasis and suggest that targeting CRIPTO/GRP78 signaling may have significant therapeutic potential.
This review delineates the zebrafish CSC-xenograft model as a useful tool for both CSC biological study and anticancer drug screening.
In this review we present describe the role of miRs in the processing of the supportive bone microenvironment prior and after the bone colonization by cancer cells. Finally, future therapeutic strategies and perspectives are also discussed.
In Holland the PhD thesis are published as small real books
Our observations suggest that miR-25 is a key regulator of invasiveness in human prostate cancer through its direct interactions with αv- and α6-integrin expression.