Eugenio Zoni
Eugenio Zoni
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miR-221
miR-221 Augments TRAIL-Mediated Apoptosis in Prostate Cancer Cells by Inducing Endogenous TRAIL Expression and Targeting the Functional Repressors SOCS3 and PIK3R1
The influence of miR-221 on TRAIL-mediated apoptosis is highly context- and entity-dependent.
miR-221-5p regulates proliferation and migration in human prostate cancer cells and reduces tumor growth in vivo
These data support a tumor suppressive role of miR-221-5p in the context of PCa and its potential as therapeutic target.
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